{"id":837,"date":"2026-05-28T09:20:22","date_gmt":"2026-05-28T09:20:22","guid":{"rendered":"https:\/\/forum-impl.iti.org\/en\/?post_type=article&#038;p=837"},"modified":"2026-06-12T12:23:46","modified_gmt":"2026-06-12T12:23:46","slug":"personalized-oral-implantology-a-definition-and-outlook-on-future-potential-7801","status":"publish","type":"article","link":"https:\/\/forum-impl.iti.org\/en\/article\/personalized-oral-implantology-a-definition-and-outlook-on-future-potential-7801\/","title":{"rendered":"Personalized Oral Implantology &#8211; a Definition and Outlook on Future Potential"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"article-type":[5],"forum-tag":[99,25,74,187,188],"class_list":["post-837","article","type-article","status-publish","hentry","article-type-feature-article","forum-tag-3d-printing","forum-tag-artificial-intelligence","forum-tag-digital-workflow","forum-tag-omics","forum-tag-personalized-dentistry"],"acf":{"feature_topic":1441,"authors":[1346,1348,1350],"read_time":"16 min","publication_date":"20250423","doi":"10.3290\/iti.fi.45753","excerpt":"This narrative review explores current aspects of personalized implantology and its clinical implementation.","references":"Alassy H, Parachuru P, Wolff L. Peri-Implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: A narrative review. Diagnostics (Basel). 2019;9(4):214\r\n\r\nBallman KV. Biomarker: Predictive or Prognostic?. J Clin Oncol. 2015;33(33):3968-3971.\r\n\r\nBartnikowski M, Vaquette C, Ivanovski S. Workflow for highly porous resorbable custom 3D printed scaffolds using medical grade polymer for large volume alveolar bone regeneration. Clin Oral Implants Res. 2020;31(5):431-441.\r\n\r\nBartold PM, Ivanovski S. P4 Medicine as a model for precision periodontal care. Clin Oral Investig. 2022;26(9):5517-5533.\r\n\r\nBornes RS, Montero J, Correia ARM, Rosa NRDN. Use of bioinformatic strategies as a predictive tool in implant-supported oral rehabilitation: A scoping review. J Prosthet Dent. 2023 Feb;129(2):322.e1-322.e8.\r\n\r\nBornstein MM, Al-Nawas B, Kuchler U, Tahmaseb A. Consensus statements and recommended clinical procedures regarding contemporary surgical and radiographic techniques in implant dentistry. Int J Oral Maxillofac Implants. 2014;29 Suppl:78-82.\r\n\r\nChen Z, Liu Y, Xie X, Deng F. Influence of bone density on the accuracy of artificial intelligence-guided implant surgery: An in vitro study. J Prosthet Dent. 2024;131(2):254-261.\r\n\r\nChiapasco M, Casentini P, Tommasato G, Dellavia C, Del Fabbro M. Customized CAD\/CAM titanium meshes for the guided bone regeneration of severe alveolar ridge defects: Preliminary results of a retrospective clinical study in humans. Clin Oral Implants Res. 2021;32(4):498-510.\r\n\r\nCollins FS, Fink L. The Human Genome Project. Alcohol Health Res World. 1995;19(3):190-195.\r\n\r\nDreyer H, Grischke J, Tiede C, et al. Epidemiology and risk factors of peri-implantitis: A systematic review. J Periodontal Res. 2018;53(5):657-681.\r\n\r\nEl Kholy K, Janner SFM, Schimmel M, Buser D. The influence of guided sleeve height, drilling distance, and drilling key length on the accuracy of static Computer-Assisted Implant Surgery. Clin Implant Dent Relat Res. 2019;21(1):101-7.\r\n\r\nEl-Danasory MB, Khamis MM, Abdel Hakim AA, Fahmy RA. CAD-CAM custom healing abutments: A dental technique. J Prosthet Dent. 2024;132(3):496-499.\r\n\r\nEuropean Union. Notices from European Union institutions, bodies, offices and agencies. [Internet]. Brussels: European Union; [cited 2024 Nov 12]. Available from: <a href=\"https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=OJ%3AC%3A2015%3A421%3AFULL\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=OJ%3AC%3A2015%3A421%3AFULL<\/a>\r\n\r\nFontenele RC, Gerhardt MDN, Picoli FF, et al. Convolutional neural network-based automated maxillary alveolar bone segmentation on cone-beam computed tomography images. Clin Oral Implants Res. 2023;34(6):565-74.\r\n\r\nGuentsch A, An H, Dentino AR. Precision and trueness of computer-assisted implant placement using static surgical guides with open and closed sleeves: An in vitro analysis. Clin Oral Implants Res. 2022;33(4):441-450.\r\n\r\nGuerrero ME, Jacobs R, Loubele M, Schutyser F, Suetens P, van Steenberghe D. State-of-the-art on cone beam CT imaging for preoperative planning of implant placement. Clin Oral Investig. 2006;10(1):1-7.\r\n\r\nHe J, Zhang Q, Wang X, et al. In vitro and in vivo accuracy of autonomous robotic vs. fully guided static computer-assisted implant surgery. Clin Implant Dent Relat Res. 2024;26(2):385-401.\r\n\r\nHeitz-Mayfield LJA, Heitz F, Lang NP. Implant Disease Risk Assessment IDRA-a tool for preventing peri-implant disease. Clin Oral Implants Res. 2020;31(4):397-403.\r\n\r\nHerrera D, Berglundh T, Schwarz F, et al. Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline. J Clin Periodontol. 2023;50 Suppl 26:4-76.\r\n\r\nHood L. Systems biology and p4 medicine: past, present, and future. Rambam Maimonides Med J. 2013;4(2):e0012. Published 2013 Apr 30.\r\n\r\nHuang M, Wang C, Li P, Lu H, Li A, Xu S. Role of immune dysregulation in peri-implantitis. Front Immunol. 2024;15:1466417. Published 2024 Nov 1.\r\n\r\nHung KF, Yeung AWK, Bornstein MM, Schwendicke F. Personalized dental medicine, artificial intelligence, and their relevance for dentomaxillofacial imaging. Dentomaxillofac Radiol. 2023;52(1):20220335.\r\n\r\nIvanovski S, Breik O, Carluccio D, Alayan J, Staples R, Vaquette C. 3D printing for bone regeneration: challenges and opportunities for achieving predictability. Periodontol 2000. 2023;93(1):358-384.\r\n\r\nJoda T, Zitzmann NU. Personalized workflows in reconstructive dentistry-current possibilities and future opportunities. Clin Oral Investig. 2022;26(6):4283-90.\r\n\r\nKabbashi S, Roomaney IA, Chetty M. Bridging the gap between omics research and dental practice. BDJ Open. 2024;10(1):16.\r\n\r\nKhaohoen A, Powcharoen W, Sornsuwan T, Chaijareenont P, Rungsiyakull C, Rungsiyakull P. Accuracy of implant placement with computer-aided static, dynamic, and robot-assisted surgery: a systematic review and meta-analysis of clinical trials. BMC Oral Health. 2024;24(1):359.\r\n\r\nKornman KS, Duff GW. Personalized medicine: will dentistry ride the wave or watch from the beach? J Dent Res. 2012;91(7 Suppl):8S-11S.\r\n\r\nLyakhov PA, Dolgalev AA, Lyakhova UA, Muraev AA, Zolotayev KE, Semerikov DY. Neural network system for analyzing statistical factors of patients for predicting the survival of dental implants. Front Neuroinform. 2022;16:1067040.\r\n\r\nMacr\u00ec M, D'Albis V, D'Albis G, et al. The role and applications of artificial intelligence in dental implant planning: A systematic review. Bioengineering (Basel). 2024;11(8):778.\r\n\r\nMcCarthy J, Minsky M, Rochester N, Shannon CE. A proposal for the Dartmouth Summer Research Project on Artificial Intelligence. 1956.\r\n\r\nMozer PS. Accuracy and deviation analysis of static and robotic guided implant surgery: a case study. Int J Oral Maxillofac Implants. 2020;35(5)\r\n\r\nNesic D, Schaefer BM, Sun Y, Saulacic N, Sailer I. 3D Printing Approach in Dentistry: The Future for Personalized Oral Soft Tissue Regeneration. J Clin Med. 2020;9(7):2238.\r\n\r\nPimkhaokham A, Chow J, Pozzi A, Arunjaroensuk S, Subbalehka K, Mattheos N. Computer-assisted and robotic implant surgery: Assessing the outcome measures of accuracy and educational implications. Clin Oral Implants Res. 2024;35(8):939-953.\r\n\r\nPirmohamed M. Pharmacogenomics: current status and future perspectives. Nat Rev Genet. 2023;24(6):350-362.\r\n\r\nRenvert S, Persson GR, Pirih FQ, Camargo PM. Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations. J Periodontol. 2018;89 Suppl 1:S304-S312.\r\n\r\nRevilla-Le\u00f3n M, G\u00f3mez-Polo M, Vyas S, et al. Artificial intelligence applications in implant dentistry: A systematic review. J Prosthet Dent. 2023;129(2):293-300.\r\n\r\nSakai T, Li H, Shimada T, et al. Development of artificial intelligence model for supporting implant drilling protocol decision making. J Prosthodont Res. 2023;67(3):360-365.\r\n\r\nSantamaria P, Troiano G, Serroni M, Ara\u00f9jo TG, Ravid\u00e0 A, Nibali L. Exploring the accuracy of tooth loss prediction between a clinical periodontal prognostic system and a machine learning prognostic model. J Clin Periodontol. 2024;51(10):1333-1341.\r\n\r\nSchwendicke F, Krois J. Data Dentistry: How Data Are Changing Clinical Care and Research. J Dent Res. 2022;101(1):21-29.\r\n\r\nShungin D, Haworth S, Divaris K, Agler CS, Kamatani Y, Keun Lee M, Grinde K, Hindy G, Alaraudanjoki V, Pesonen P, Teumer A, Holtfreter B, Sakaue S, Hirata J, Yu Y-H, Ridker PM, Giulianini F, Chasman DI, Magnusson PKE, Johansson I. Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Nat Commun. 2019;10(1):2773\r\n\r\nSouza AB, Alshihri A, K\u00e4mmerer PW, Ara\u00fajo MG, Gallucci GO. Histological and micro-CT analysis of peri-implant soft and hard tissue healing on implants with different healing abutments configurations. Clin Oral Implants Res. 2018;29(10):1007-1015.\r\n\r\nTahmaseb A, Wu V, Wismeijer D, Coucke W, Evans C. The accuracy of static computer-aided implant surgery: A systematic review and meta-analysis. Clin Oral Implants Res. 2018;29 Suppl 16:416-435.\r\n\r\nTommasato G, Piano S, Casentini P, De Stavola L, Chiapasco M. Digital planning and bone regenerative technologies: A narrative review. Clin Oral Implants Res. 2024;35(8):906-921.\r\n\r\nVinnakota DN, Kamatham R, Nagaraj E, Reddy PS. Is dynamic computer-assisted surgery more accurate than the static method for dental implant placement? A systematic review and meta-analysis. J Prosthet Dent. 2023 Sep 8.\r\n\r\nWang J, Wang B, Liu YY, Luo YL, Wu YY, Xiang L, Yang XM, Qu YL, Tian TR, Man Y. Recent Advances in Digital Technology in Implant Dentistry. J Dent Res. 2024 Jul;103(8):787-799. doi: 10.1177\/00220345241253794. Epub 2024 May 31. PMID: 38822563.\r\n\r\nWang CW, Hao Y, Di Gianfilippo R, et al. Machine learning-assisted immune profiling stratifies peri-implantitis patients with unique microbial colonization and clinical outcomes. Theranostics. 2021;11(14):6703-6716.\r\n\r\nXu, C., Ivanovski, S. Clinical translation of personalized bioengineered implant scaffolds. Nat Rev Bioeng (2025). <a href=\"https:\/\/doi.org\/10.1038\/s44222-024-00269-z\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1038\/s44222-024-00269-z<\/a>\r\n\r\nYang S, Chen J, Li A, Li P, Xu S. Autonomous Robotic Surgery for Immediately Loaded Implant-Supported Maxillary Full-Arch Prosthesis: A Case Report. J Clin Med. 2022;11(21):6594.\r\n\r\nYang W, Chen D, Wang C, et al. The effect of bone defect size on the 3D accuracy of alveolar bone augmentation performed with additively manufactured patient-specific titanium mesh. BMC Oral Health. 2022;22(1):557.\r\n\r\nZhang L, Henson BS, Camargo PM, Wong DT. The clinical value of salivary biomarkers for periodontal disease. Periodontol 2000. 2009;51:25-37.\r\n\r\nWerny JG, Fan S, Diaz L, et al. Evaluation of the Accuracy, Surgical Time, and Learning Curve of Freehand, Static, and Dynamic Computer-Assisted Implant Surgery in an In Vitro Study. Clin Oral Implants Res. Published online January 21, 2025.","endnote":"OWN - ITI International Team for Implantology\r\n CI - ITI International Team for Implantology\r\n JT - Forum Implantologicum\r\n DP - 2025\r\n LA - en\r\n TI - Personalized Oral Implantology - a Definition and Outlook on Future Potential\r\nOWN - ITI International Team for Implantology\r\n AU - Ivanovski S.\r\n AU - Pereira da Mata Santos R.\r\n AU - Arora H.\r\nAID - 10.3290\/iti.fi.45753[doi]\r\n AB - Abstract"},"_links":{"self":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/837","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article"}],"about":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/types\/article"}],"version-history":[{"count":4,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/837\/revisions"}],"predecessor-version":[{"id":1747,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/837\/revisions\/1747"}],"acf:post":[{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1350"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1348"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1346"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/feature-topic\/1441"}],"wp:attachment":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/media?parent=837"}],"wp:term":[{"taxonomy":"article-type","embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article-type?post=837"},{"taxonomy":"forum-tag","embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-tag?post=837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}