{"id":941,"date":"2026-05-28T10:01:22","date_gmt":"2026-05-28T10:01:22","guid":{"rendered":"https:\/\/forum-impl.iti.org\/en\/?post_type=article&p=941"},"modified":"2026-06-16T11:21:42","modified_gmt":"2026-06-16T11:21:42","slug":"use-of-laser-therapy-for-periimplantitis-6401","status":"publish","type":"article","link":"https:\/\/forum-impl.iti.org\/en\/article\/use-of-laser-therapy-for-periimplantitis-6401\/","title":{"rendered":"Use of Laser Therapy for Peri-implantitis"},"content":{"rendered":"","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"article-type":[5],"forum-tag":[48,269,270,153,271],"class_list":["post-941","article","type-article","status-publish","hentry","article-type-feature-article","forum-tag-dental-implants","forum-tag-disease-management","forum-tag-laser","forum-tag-peri-implantitis","forum-tag-success"],"acf":{"feature_topic":1442,"authors":[1311,1313,1315],"read_time":"20 min","publication_date":"20240828","doi":"10.3290\/iti.fi.45738","excerpt":"A guideline for laser-assisted peri-implantitis therapy to guide clinicians on when, how and what types of lasers can be applied to assist peri-implantitis treatment.","references":"Aimetti, M, Mariani, G. M, Ferrarotti, F, Ercoli, E, Liu, C. C, & Romano, F. (2019). Adjunctive efficacy of diode laser in the treatment of peri-implant mucositis with mechanical therapy: A randomized clinical trial. Clinical Oral Implants Research, 30(5), 429\u2013438. https:\/\/doi.org\/10.1111\/clr.13428\r\n\r\nAlbaker, A. M, ArRejaie, A. S, Alrabiah, M, & Abduljabbar, T. (2018). Effect of photodynamic and laser therapy in the treatment of peri-implant mucositis: A systematic review. Photodiagnosis and Photodynamic Therapy, 21, 147\u2013152. https:\/\/doi.org\/10.1016\/j.pdpdt.2017.11.011\r\n\r\nAlbertini, R, Aimbire, F, Villaverde, A. B, Silva, J. A, & Costa, M. S. (2007). COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.], 56(6), 228\u2013229. https:\/\/doi.org\/10.1007\/s00011-007-6211-6\r\n\r\nAlbertini, R, Villaverde, A. B, Aimbire, F, Salgado, M. A. C, Bjordal, J. M, Alves, L. P, Munin, E, & Costa, M. S. (2007). Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660nm and 684nm) in carrageenan-induced rat paw edema. Journal of Photochemistry and Photobiology B: Biology, 89(1), 50\u201355. https:\/\/doi.org\/10.1016\/j.jphotobiol.2007.08.005\r\n\r\nAleksic, V, Aoki, A, Iwasaki, K, Takasaki, A. A, Wang, C.-Y, Abiko, Y, Ishikawa, I, & Izumi, Y. (2010). Low-level Er:YAG laser irradiation enhances osteoblast proliferation through activation of MAPK\/ERK. Lasers in Medical Science, 25(4), 559\u2013569. https:\/\/doi.org\/10.1007\/s10103-010-0761-5\r\n\r\nAlpaslan Yayli, N. Z, Talmac, A. C, Keskin Tunc, S, Akbal, D, Altindal, D, & Ertugrul, A. S. (2022). Erbium, chromium-doped: Yttrium, scandium, gallium, garnet and diode lasers in the treatment of peri-implantitis: clinical and biochemical outcomes in a randomized-controlled clinical trial. Lasers in Medical Science, 37(1), 665\u2013674. https:\/\/doi.org\/10.1007\/s10103-021-03436-5\r\n\r\nAoki, A, Miura, M, Akiyama, F, Nakagawa, N, Tanaka, J, Oda, S, Watanabe, H, & Ishikawa, I. (2000). In vitro evaluation of Er:YAG laser scaling of subgingival calculus in comparison with ultrasonic scaling. Journal of Periodontal Research, 35(5), 266\u2013277. https:\/\/doi.org\/10.1034\/j.1600-0765.2000.035005266.x\r\n\r\nAoki, A, Mizutani, K, Schwarz, F, Sculean, A, Yukna, R. A, Takasaki, A. A, Romanos, G. E, Taniguchi, Y, Sasaki, K. M, Zeredo, J. L, Koshy, G, Coluzzi, D. J, White, J. M, Abiko, Y, Ishikawa, I, & Izumi, Y. (2015). Periodontal and peri-implant wound healing following laser therapy. Periodontology 2000, 68(1), 217\u2013269. https:\/\/doi.org\/10.1111\/prd.12080\r\n\r\nAoki, A, Sasaki, K. M, Watanabe, H, & Ishikawa, I. (2004). Lasers in nonsurgical periodontal therapy. Periodontology 2000, 36, 59\u201397. https:\/\/doi.org\/10.1111\/j.1600-0757.2004.03679.x\r\n\r\nAsnaashari, M, & Safavi, N. (2013). Application of Low level Lasers in Dentistry (Endodontic). Journal of Lasers in Medical Sciences, 4(2), 57\u201366.\r\n\r\nBlanco, C, Pico, A, Dopico, J, G\u00e1ndara, P, Blanco, J, & Li\u00f1ares, A. (2022). Adjunctive benefits of systemic metronidazole on non-surgical treatment of peri-implantitis. A randomized placebo-controlled clinical trial. Journal of Clinical Periodontology, 49(1), 15\u201327. https:\/\/doi.org\/10.1111\/jcpe.13564\r\n\r\nChan, H.-L, Rodriguez Betancourt, A, Liu, C. C, Chiang, Y.-C, & Schmidlin, P. R. (2023). A conceptual review on reconstructive peri-implantitis therapy: Challenges and opportunities. Clinical and Experimental Dental Research, 9(5), 735\u2013745. https:\/\/doi.org\/10.1002\/cre2.788\r\n\r\nClem, D, & Gunsolley, J. C. (2019). Peri-implantitis Treatment Using Er:YAG Laser and Bone Grafting. A Prospective Consecutive Case Series Evaluation: 1 Year Posttherapy. The International Journal of Periodontics & Restorative Dentistry, 39(4), 479\u2013489. https:\/\/doi.org\/10.11607\/prd.4158\r\n\r\nCosgarea, R, Roccuzzo, A, Jepsen, K, Sculean, A, Jepsen, S, & Salvi, G. E. (2022). Efficacy of mechanical\/physical approaches for implant surface decontamination in non-surgical submarginal instrumentation of peri-implantitis. A systematic review. Journal of Clinical Periodontology, n\/a(n\/a). https:\/\/doi.org\/10.1111\/jcpe.13762\r\n\r\nCrespi, R, Marconcini, S, Crespi, G, Giammarinaro, E, Menchini Fabris, G. B, Barone, A, & Covani, U. (2019). Nonsurgical Treatment of Peri-implantitis Without Eliminating Granulation Tissue: A 3-Year Study. Implant Dentistry, 28(1), 4\u201310. https:\/\/doi.org\/10.1097\/ID.0000000000000832\r\n\r\nde Freitas, L. F, & Hamblin, M. R. (2016). Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy. IEEE Journal of Selected Topics in Quantum Electronics: A Publication of the IEEE Lasers and Electro-Optics Society, 22(3), 7000417. https:\/\/doi.org\/10.1109\/JSTQE.2016.2561201\r\n\r\nDe Waal, Y. C. M, Vangsted, T. E, & Van Winkelhoff, A. J. (2021). Systemic antibiotic therapy as an adjunct to non-surgical peri-implantitis treatment: A single-blind RCT. Journal of Clinical Periodontology, 48(7), 996\u20131006. https:\/\/doi.org\/10.1111\/jcpe.13464\r\n\r\nDeppe, H, Ahrens, M, Behr, A. V, Marr, C, Sculean, A, Mela, P, & Ritschl, L. M. (2021). Thermal effect of a 445 nm diode laser on five dental implant systems: An in vitro study. Scientific Reports, 11(1), Article 1. https:\/\/doi.org\/10.1038\/s41598-021-99709-8\r\n\r\nDerks, J, Schaller, D, H\u00e5kansson, J, Wennstr\u00f6m, J. L, Tomasi, C, & Berglundh, T. (2016). Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis. Journal of Dental Research, 95(1), 43\u201349. https:\/\/doi.org\/10.1177\/0022034515608832\r\n\r\nDi Gianfilippo, R, Wang, C.-W, Xie, Y, Kinney, J, Sugai, J, Giannobile, W. V, & Wang, H.-L. (2023). Effect of laser-assisted reconstructive surgical therapy of peri-implantitis on protein biomarkers and bacterial load. Clinical Oral Implants Research, 34(4), 393\u2013403. https:\/\/doi.org\/10.1111\/clr.14059\r\n\r\nDiaz, P, Gonzalo, E, Villagra, L. J. G, Miegimolle, B, & Suarez, M. J. (2022). What is the prevalence of peri-implantitis? A systematic review and meta-analysis. BMC Oral Health, 22(1), 449. https:\/\/doi.org\/10.1186\/s12903-022-02493-8\r\n\r\nEriksson, A. R, & Albrektsson, T. (1983). Temperature threshold levels for heat-induced bone tissue injury: A vital-microscopic study in the rabbit. The Journal of Prosthetic Dentistry, 50(1), 101\u2013107. https:\/\/doi.org\/10.1016\/0022-3913(83)90174-9\r\n\r\nFiguero, E, Graziani, F, Sanz, I, Herrera, D, & Sanz, M. (2014). Management of peri-implant mucositis and peri-implantitis. Periodontology 2000, 66(1), 255\u2013273. https:\/\/doi.org\/10.1111\/prd.12049\r\n\r\nFragkioudakis, I, Kallis, A, Kesidou, E, Damianidou, O, Sakellari, D, & Vouros, I. (2023). Surgical Treatment of Peri-Implantitis Using a Combined Nd: YAG and Er: YAG Laser Approach: Investigation of Clinical and Bone Loss Biomarkers. Dentistry Journal, 11(3), Article 3. https:\/\/doi.org\/10.3390\/dj11030061\r\n\r\nGavish, L, Rubinstein, C, Berlatzky, Y, Gavish, L. Y, Beeri, R, Gilon, D, Bulut, A, Harlev, M, Reissman, P, & Gertz, S. D. (2012). Low level laser arrests abdominal aortic aneurysm by collagen matrix reinforcement in apolipoprotein E-deficient mice. Lasers in Surgery and Medicine, 44(8), 664\u2013674. https:\/\/doi.org\/10.1002\/lsm.22068\r\n\r\nGholami, G. A, Karamlou, M, Fekrazad, R, Ghanavati, F, Hakimiha, N, & Romanos, G. (2018). Comparison of the Effects of Er, Cr: YSGG Laser and Super-Saturated Citric Acid on the Debridement of Contaminated Implant Surfaces. Journal of Lasers in Medical Sciences, 9(4), 254\u2013260. https:\/\/doi.org\/10.15171\/jlms.2018.46\r\n\r\nHamajima, S, Hiratsuka, K, Kiyama-Kishikawa, M, Tagawa, T, Kawahara, M, Ohta, M, Sasahara, H, & Abiko, Y. (2003). Effect of low-level laser irradiation on osteoglycin gene expression in osteoblasts. Lasers in Medical Science, 18(2), 78\u201382. https:\/\/doi.org\/10.1007\/s10103-003-0255-9\r\n\r\nHauser-Gerspach, I, St\u00fcbinger, S, & Meyer, J. (2010). Bactericidal effects of different laser systems on bacteria adhered to dental implant surfaces: An in vitro study comparing zirconia with titanium. Clinical Oral Implants Research, 21(3), 277\u2013283. https:\/\/doi.org\/10.1111\/j.1600-0501.2009.01835.x\r\n\r\nHerrera, D, Berglundh, T, Schwarz, F, Chapple, I, Jepsen, S, Sculean, A, Kebschull, M, Papapanou, P. N, Tonetti, M. S, Sanz, M, & EFP workshop participants and methodological consultant. (2023). Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline. Journal of Clinical Periodontology, 50 Suppl 26, 4\u201376. https:\/\/doi.org\/10.1111\/jcpe.13823\r\n\r\nJoshi, A. A, Gaikwad, A. M, Padhye, A. M, & Nadgere, J. B. (2022). Overview of Systematic Reviews and Meta-analyses Investigating the Efficacy of Different Nonsurgical Therapies for the Treatment of Peri-implant Diseases. The International Journal of Oral & Maxillofacial Implants, 37(1), e13\u2013e27. https:\/\/doi.org\/10.11607\/jomi.9088\r\n\r\nKang, P, Sanz-Miralles, E, Li, J, Linden, E, & Momen-Heravi, F. (2023). Efficacy of Er,Cr:YSGG Laser Application in Nonsurgical Treatment of Peri-implantitis: A Human Randomized Controlled Trial. The International Journal of Periodontics & Restorative Dentistry, 43(1), e1\u2013e9. https:\/\/doi.org\/10.11607\/prd.6384\r\n\r\nKaroussis, I. K, Kyriakidou, K, Psarros, C, Lang, N. P, & Vrotsos, I. A. (2017). Nd:YAG laser radiation (1.064 nm) accelerates differentiation of osteoblasts to osteocytes on smooth and rough titanium surfaces in vitro. Clinical Oral Implants Research, 28(7), 785\u2013790. https:\/\/doi.org\/10.1111\/clr.12882\r\n\r\nKato, T, Kusakari, H, & Hoshino, E. (1998). Bactericidal efficacy of carbon dioxide laser against bacteria-contaminated titanium implant and subsequent cellular adhesion to irradiated area. Lasers in Surgery and Medicine, 23(5), 299\u2013309. https:\/\/doi.org\/10.1002\/(sici)1096-9101(1998)23:5<299::aid-lsm10>3.0.co;2-k\r\n\r\nKreisler, M, G\u00f6tz, H, & Duschner, H. (2002). Effect of Nd:YAG, Ho:YAG, Er:YAG, CO2, and GaAIAs laser irradiation on surface properties of endosseous dental implants. The International Journal of Oral & Maxillofacial Implants, 17(2), 202\u2013211.\r\n\r\nLi, L, Deng, J, & Ren, S. (2021). The clinical efficacy of Er:YAG lasers in the treatment of peri-implantitis: A systematic review and meta-analysis. Annals of Palliative Medicine, 10(8), 9002\u20139014. https:\/\/doi.org\/10.21037\/apm-21-1853\r\n\r\nLin, G.-H, F, S. L. D. A, & Hl, W. (2018). Laser therapy for treatment of peri-implant mucositis and peri-implantitis: An American Academy of Periodontology best evidence review. Journal of Periodontology, 89(7), 766\u2013782. https:\/\/doi.org\/10.1902\/jop.2017.160483\r\n\r\nLin, T, Taniguchi, Y, Aoki, A, & Chang, Y.-C. (2019). Clinical evaluation of multiple peri-implant bony defect management by Er:YAG laser-assisted bone regenerative therapy. Journal of Dental Sciences, 14(4), 430\u2013432. https:\/\/doi.org\/10.1016\/j.jds.2019.07.001\r\n\r\nLin, T, Taniguchi, Y, Aoki, A, & Chen, C.-C. (2021). The \u201cEr:YAG laser-assisted periimplantitis total therapy (Er:LPTT)\u201d-a novel procedure to perform periimplantitis treatment with bone regeneration therapy. Journal of Dental Sciences, 16(4), 1302\u20131304. https:\/\/doi.org\/10.1016\/j.jds.2021.05.006\r\n\r\nLin, T, Yu, C.-C, Liu, C.-M, Hsieh, P.-L, Liao, Y.-W, Yu, C.-H, & Chen, C.-J. (2021). Er:YAG laser promotes proliferation and wound healing capacity of human periodontal ligament fibroblasts through Galectin-7 induction. Journal of the Formosan Medical Association = Taiwan Yi Zhi, 120(1 Pt 2), 388\u2013394. https:\/\/doi.org\/10.1016\/j.jfma.2020.06.005\r\n\r\nLinden, E, Cobb, C. M, Fletcher, P, & Zhao, D. (2021). SEM Evaluation of the Effects of Laser-Mediated Implant Surface Decontamination: An In Situ Human Pilot Study. The International Journal of Periodontics & Restorative Dentistry, 41(5), 711\u2013717. https:\/\/doi.org\/10.11607\/prd.4911\r\n\r\nListl, S, Fr\u00fchauf, N, Dannewitz, B, Weis, C, Tu, Y.-K, Chang, H.-J, & Faggion, C. M. (2015). Cost-effectiveness of non-surgical peri-implantitis treatments. Journal of Clinical Periodontology, 42(5), 470\u2013477. https:\/\/doi.org\/10.1111\/jcpe.12402\r\n\r\nMatsuyama, T, Aoki, A, Oda, S, Yoneyama, T, & Ishikawa, I. (2003). Effects of the Er:YAG laser irradiation on titanium implant materials and contaminated implant abutment surfaces. Journal of Clinical Laser Medicine & Surgery, 21(1), 7\u201317. https:\/\/doi.org\/10.1089\/10445470360516680\r\n\r\nMcGuff, P. E, Deterling, R. A, & Gottlieb, L. S. (1965). Tumoricidal effect of laser energy on experimental and human malignant tumors. The New England Journal of Medicine, 273(9), 490\u2013492. https:\/\/doi.org\/10.1056\/NEJM196508262730906\r\n\r\nMisischia, W. P, Xenoudi, P, Yukna, R. A, & Schurr, M. J. (2021). Bacterial reduction effect of four different dental lasers on titanium surfaces in vitro. Lasers in Medical Science, 36(8), 1759\u20131767. https:\/\/doi.org\/10.1007\/s10103-021-03349-3\r\n\r\nMizutani, K, Aoki, A, Coluzzi, D, Yukna, R, Wang, C.-Y, Pavlic, V, & Izumi, Y. (2016). Lasers in minimally invasive periodontal and peri-implant therapy. Periodontology 2000, 71(1), 185\u2013212. https:\/\/doi.org\/10.1111\/prd.12123\r\n\r\nMonje, A, Amerio, E, Jae Kook Cha, Kotsakis, G, Pons, R, Renvert, S, Sanz-Martin, I, Schwarz, F, Sculean, A, Stavropoulos, A, Tarnow, D, & Hom-Lay Wang. (2022). Strategies for implant surface decontamination in peri-implantitis therapy. International Journal of Oral Implantology, 15(3), 213\u2013248.\r\n\r\nMonje, A, Pons, R, Insua, A, Nart, J, Wang, H.-L, & Schwarz, F. (2019). Morphology and severity of peri-implantitis bone defects. Clinical Implant Dentistry and Related Research, 21(4), 635\u2013643. https:\/\/doi.org\/10.1111\/cid.12791\r\n\r\nMonzavi, A, Shahabi, S, Fekrazad, R, Behruzi, R, & Chiniforush, N. (2014). Implant Surface Temperature Changes during Er:YAG Laser Irradiation with Different Cooling Systems. Journal of Dentistry (Tehran, Iran), 11(2), 210\u2013215.\r\n\r\nMorlock, B. J, Pippin, D. J, Cobb, C. M, Killoy, W. J, & Rapley, J. W. (1992). The effect of Nd:YAG laser exposure on root surfaces when used as an adjunct to root planing: An in vitro study. Journal of Periodontology, 63(7), 637\u2013641. https:\/\/doi.org\/10.1902\/jop.1992.63.7.637\r\n\r\nMouhyi, J, Sennerby, L, Nammour, S, Guillaume, P, & Van Reck, J. (1999). Temperature increases during surface decontamination of titanium implants using CO2 laser. Clinical Oral Implants Research, 10(1), 54\u201361. https:\/\/doi.org\/10.1034\/j.1600-0501.1999.100107.x\r\n\r\nNaeimi Darestani, M, Houshmand, B, Mosaddad, S. A, & Talebi, M. (2023). Assessing the Surface Modifications of Contaminated Sandblasted and Acid-Etched Implants Through Diode Lasers of Different Wavelengths: An In Vitro Study. Photobiomodulation, Photomedicine, and Laser Surgery, 41(5), 201\u2013211. https:\/\/doi.org\/10.1089\/photob.2023.0009\r\n\r\nNevins, M, Benfenati, S. P, Galletti, P, Zuchi, A, Sava, C, Sava, C, Trifan, M, Piattelli, A, Lezzi, G, Chen, C.-Y, Kim, D. M, & Rocchietta, I. (2020). Human Histologic Evaluations of the Use of Er,Cr:YSGG Laser to Decontaminate an Infected Dental Implant Surface in Preparation for Implant Reosseointegration. The International Journal of Periodontics & Restorative Dentistry, 40(6), 805\u2013812. https:\/\/doi.org\/10.11607\/prd.5139\r\n\r\nNevins, M, Nevins, M. L, Yamamoto, A, Yoshino, T, Ono, Y, Wang, C.-W, & Kim, D. M. (2014). Use of Er:YAG laser to decontaminate infected dental implant surface in preparation for reestablishment of bone-to-implant contact. The International Journal of Periodontics & Restorative Dentistry, 34(4), 461\u2013466. https:\/\/doi.org\/10.11607\/prd.2192\r\n\r\nNg, M. Y, Lin, T, Chen, S.-H, Liao, Y.-W, Liu, C.-M, & Yu, C.-C. (2024). Er:YAG laser suppresses pro-inflammatory cytokines expression and inflammasome in human periodontal ligament fibroblasts with Porphyromonas gingivalis-lipopolysaccharide stimulation. Journal of Dental Sciences. https:\/\/doi.org\/10.1016\/j.jds.2023.12.011\r\n\r\nPapadopoulos, C. A, Vouros, I, Menexes, G, & Konstantinidis, A. (2015). The utilization of a diode laser in the surgical treatment of peri-implantitis. A randomized clinical trial. Clinical Oral Investigations, 19(8), 1851\u20131860. https:\/\/doi.org\/10.1007\/s00784-014-1397-9\r\n\r\nParma-Benfenati, S, Roncati, M, & Tinti, C. (2013). Treatment of peri-implantitis: Surgical therapeutic approaches based on peri-implantitis defects. The International Journal of Periodontics & Restorative Dentistry, 33(5), 627\u2013633. https:\/\/doi.org\/10.11607\/prd.1549\r\n\r\nPires, D, Xavier, M, Ara\u00fajo, T, Silva, J. A, Aimbire, F, & Albertini, R. (2011). Low-level laser therapy (LLLT; 780 nm) acts differently on mRNA expression of anti- and pro-inflammatory mediators in an experimental model of collagenase-induced tendinitis in rat. Lasers in Medical Science, 26(1), 85\u201394. https:\/\/doi.org\/10.1007\/s10103-010-0811-z\r\n\r\nPirnat, S, Lukac, M, & Ihan, A. (2011). Study of the direct bactericidal effect of Nd:YAG and diode laser parameters used in endodontics on pigmented and nonpigmented bacteria. Lasers in Medical Science, 26(6), 755\u2013761. https:\/\/doi.org\/10.1007\/s10103-010-0808-7\r\n\r\nRamanauskaite, A, Fretwurst, T, & Schwarz, F. (2021). Efficacy of alternative or adjunctive measures to conventional non-surgical and surgical treatment of peri-implant mucositis and peri-implantitis: A systematic review and meta-analysis. International Journal of Implant Dentistry, 7(1), 112. https:\/\/doi.org\/10.1186\/s40729-021-00388-x\r\n\r\nRavid\u00e0, A, Galli, M, Siqueira, R, Saleh, M. H. A, Galindo-Moreno, P, & Wang, H.-L. (2020). Diagnosis of peri-implant status after peri-implantitis surgical treatment: Proposal of a new classification. Journal of Periodontology, 91(12), 1553\u20131561. https:\/\/doi.org\/10.1002\/JPER.20-0124\r\n\r\nRenvert, S, Lindahl, C, Roos Jans\u00e5ker, A.-M, & Persson, G. R. (2011). Treatment of peri-implantitis using an Er:YAG laser or an air-abrasive device: A randomized clinical trial. Journal of Clinical Periodontology, 38(1), 65\u201373. https:\/\/doi.org\/10.1111\/j.1600-051X.2010.01646.x\r\n\r\nRoccuzzo, A, Klossner, S, St\u00e4hli, A, Imber, J.-C, Eick, S, Sculean, A, & Salvi, G. E. (2022). Non-surgical mechanical therapy of peri-implantitis with or without repeated adjunctive diode laser application. A 6-month double-blinded randomized clinical trial. Clinical Oral Implants Research, 33(9), 900\u2013912. https:\/\/doi.org\/10.1111\/clr.13969\r\n\r\nRomanos, G. E, Everts, H, & Nentwig, G. H. (2000). Effects of diode and Nd:YAG laser irradiation on titanium discs: A scanning electron microscope examination. Journal of Periodontology, 71(5), 810\u2013815. https:\/\/doi.org\/10.1902\/jop.2000.71.5.810\r\n\r\nSarmiento, H. L, Norton, M, Korostoff, J, Ko, K. I, & Fiorellini, J. P. (2018). Surgical Alternatives for Treating Peri-implantitis. The International Journal of Periodontics & Restorative Dentistry, 38(5), 665\u2013671. https:\/\/doi.org\/10.11607\/prd.3639\r\n\r\nSchwarz, F, Bieling, K, Bonsmann, M, Latz, T, & Becker, J. (2006). Nonsurgical treatment of moderate and advanced periimplantitis lesions: A controlled clinical study. Clinical Oral Investigations, 10(4), 279\u2013288. https:\/\/doi.org\/10.1007\/s00784-006-0070-3\r\n\r\nSchwarz, F, Derks, J, Monje, A, & Wang, H.-L. (2018). Peri-implantitis. Journal of Periodontology, 89 Suppl 1, S267\u2013S290. https:\/\/doi.org\/10.1002\/JPER.16-0350\r\n\r\nSchwarz, F, John, G, Hegewald, A, & Becker, J. (2015). Non-surgical treatment of peri-implant mucositis and peri-implantitis at zirconia implants: A prospective case series. Journal of Clinical Periodontology, 42(8), 783\u2013788. https:\/\/doi.org\/10.1111\/jcpe.12439\r\n\r\nSchwarz, F, Olivier, W, Herten, M, Sager, M, Chaker, A, & Becker, J. (2007). Influence of implant bed preparation using an Er:YAG laser on the osseointegration of titanium implants: A histomorphometrical study in dogs. Journal of Oral Rehabilitation, 34(4), 273\u2013281. https:\/\/doi.org\/10.1111\/j.1365-2842.2006.01704.x\r\n\r\nSchwarz, F, Rothamel, D, & Becker, J. (2003). [Influence of an Er:YAG laser on the surface structure of titanium implants]. Schweizer Monatsschrift Fur Zahnmedizin = Revue Mensuelle Suisse D\u2019odonto-Stomatologie = Rivista Mensile Svizzera Di Odontologia E Stomatologia, 113(6), 660\u2013671.\r\n\r\nSchwarz, F, Sahm, N, Iglhaut, G, & Becker, J. (2011). Impact of the method of surface debridement and decontamination on the clinical outcome following combined surgical therapy of peri-implantitis: A randomized controlled clinical study. Journal of Clinical Periodontology, 38(3), 276\u2013284. https:\/\/doi.org\/10.1111\/j.1600-051X.2010.01690.x\r\n\r\nSchwarz, F, Sahm, N, Schwarz, K, & Becker, J. (2010). Impact of defect configuration on the clinical outcome following surgical regenerative therapy of peri-implantitis. Journal of Clinical Periodontology, 37(5), 449\u2013455. https:\/\/doi.org\/10.1111\/j.1600-051X.2010.01540.x\r\n\r\nSchwarz, F, Sculean, A, Berakdar, M, Szathmari, L, Georg, T, & Becker, J. (2003). In vivo and in vitro effects of an Er:YAG laser, a GaAlAs diode laser, and scaling and root planing on periodontally diseased root surfaces: A comparative histologic study. Lasers in Surgery and Medicine, 32(5), 359\u2013366. https:\/\/doi.org\/10.1002\/lsm.10179\r\n\r\nStrauss, G, Goteiner, D, Murawski, K, Singer, S. R, Drew, H. J, & Sullivan, A. (2021). Laser-Assisted Therapy for the Treatment of Peri-implantitis. Part I. Clinical Outcomes. The International Journal of Periodontics & Restorative Dentistry, 41(4), 563\u2013568. https:\/\/doi.org\/10.11607\/prd.5377\r\n\r\nStrever, J. M, Lee, J, Ealick, W, Peacock, M, Shelby, D, Susin, C, Mettenberg, D, El-Awady, A, Rueggeberg, F, & Cutler, C. W. (2017). Erbium, Chromium:Yttrium-Scandium-Gallium-Garnet Laser Effectively Ablates Single-Species Biofilms on Titanium Disks Without Detectable Surface Damage. Journal of Periodontology, 88(5), 484\u2013492. https:\/\/doi.org\/10.1902\/jop.2016.160529\r\n\r\nTakagi, T, Aoki, A, Ichinose, S, Taniguchi, Y, Tachikawa, N, Shinoki, T, Meinzer, W, Sculean, A, & Izumi, Y. (2018). Effective removal of calcified deposits on microstructured titanium fixture surfaces of dental implants with erbium lasers. Journal of Periodontology, 89(6), 680\u2013690. https:\/\/doi.org\/10.1002\/JPER.17-0389\r\n\r\nTakasaki, A. A, Aoki, A, Mizutani, K, Kikuchi, S, Oda, S, & Ishikawa, I. (2007). Er:YAG laser therapy for peri-implant infection: A histological study. Lasers in Medical Science, 22(3), 143\u2013157. https:\/\/doi.org\/10.1007\/s10103-006-0430-x\r\n\r\nTenore, G, Montori, A, Mohsen, A, Mattarelli, G, Palaia, G, & Romeo, U. (2020). Evaluation of adjunctive efficacy of diode laser in the treatment of peri-implant mucositis: A randomized clinical trial. Lasers in Medical Science, 35(6), 1411\u20131417. https:\/\/doi.org\/10.1007\/s10103-020-03009-y\r\n\r\nTing, C.-C, Fukuda, M, Watanabe, T, Aoki, T, Sanaoka, A, & Noguchi, T. (2007). Effects of Er,Cr:YSGG laser irradiation on the root surface: Morphologic analysis and efficiency of calculus removal. Journal of Periodontology, 78(11), 2156\u20132164. https:\/\/doi.org\/10.1902\/jop.2007.070160\r\n\r\nTucker, D, Cobb, C. M, Rapley, J. W, & Killoy, W. J. (1996). Morphologic changes following in vitro CO2 laser treatment of calculus-ladened root surfaces. Lasers in Surgery and Medicine, 18(2), 150\u2013156. https:\/\/doi.org\/10.1002\/(SICI)1096-9101(1996)18:2<150::AID-LSM4>3.0.CO;2-R\r\n\r\nUrban, I. A, Chen, Z, & Wang, H.-L. (2024). Decision Tree for Reconstructive Treatment of Peri-implantitis Defects. The International Journal of Periodontics & Restorative Dentistry, 0(0), 1\u201322. https:\/\/doi.org\/10.11607\/prd.7205\r\n\r\nWang, C.-W, Renvert, S, & Wang, H.-L. (2019). Nonsurgical Treatment of Periimplantitis. Implant Dentistry, 28(2), 155\u2013160. https:\/\/doi.org\/10.1097\/ID.0000000000000846\r\n\r\nWang, C.-Y, Lee, B.-S, Jhang, Y.-T, Ma, K. S.-K, Huang, C.-P, Fu, K.-L, Lai, C.-H, Tseng, W.-Y, Kuo, M. Y.-P, & Chen, Y.-W. (2021). Er:YAG laser irradiation enhances bacterial and lipopolysaccharide clearance and human gingival fibroblast adhesion on titanium discs. Scientific Reports, 11(1), 23954. https:\/\/doi.org\/10.1038\/s41598-021-03434-1\r\n\r\nWen, S.-C, Barootchi, S, Huang, W.-X, & Wang, H.-L. (2022). Surgical reconstructive treatment for infraosseous peri-implantitis defects with a submerged healing approach: A prospective controlled study. Journal of Periodontology, 93(2), 195\u2013207. https:\/\/doi.org\/10.1002\/JPER.21-0161\r\n\r\nWen, S.-C, Barootchi, S, Wang, H.-L, & Huang, W.-X. (2022). Non-submerged reconstructive approach for peri-implantitis osseous defect with removal of implant crowns: One-year outcomes of a prospective case series study. Journal of Periodontology, 93(8), 1250\u20131261. https:\/\/doi.org\/10.1002\/JPER.21-0502\r\n\r\nYamamoto, A, Kubota, T, Komatsu, Y, Nohno, K, Yasuda, T, Takahashi, T, Torikata, R, Tsumori, N, Shibutani, T, Umeda, M, & Yoshie, H. (2021). Efficacy of Erbium:YAG Laser for Regenerative Surgical Treatment of Peri-implantitis: Clinical, Microbiological, and Biomarker Analyses. The International Journal of Periodontics & Restorative Dentistry, 41(2), 187\u2013192. https:\/\/doi.org\/10.11607\/prd.4071\r\n\r\nYao, W.-L, Lin, J. C. Y, Salamanca, E, Pan, Y.-H, Tsai, P.-Y, Leu, S.-J, Yang, K.-C, Huang, H.-M, Huang, H.-Y, & Chang, W.-J. (2020). Er,Cr:YSGG Laser Performance Improves Biological Response on Titanium Surfaces. Materials (Basel, Switzerland), 13(3), 756. https:\/\/doi.org\/10.3390\/ma13030756\r\n\r\nYin, K, Zhu, R, Wang, S, & Zhao, R. C. (2017). Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells. Stem Cells and Development, 26(10), 762\u2013775. https:\/\/doi.org\/10.1089\/scd.2016.0332\r\n\r\nZampa, E. P, Kyriakidou, K, Papaparaskevas, J, Pepelassi, E, & Karoussis, I. K. (2023). Effect of Low-Level Laser Irradiation (810 nm) on the Proliferation and Differentiation of Osteoblast-Like Cells Cultured on SLA Titanium Discs Exposed to a Peri-implantitis Environment. Journal of Lasers in Medical Sciences, 14, e57. https:\/\/doi.org\/10.34172\/jlms.2023.57","endnote":"OWN - ITI International Team for Implantology\r\n CI - ITI International Team for Implantology\r\n JT - Forum Implantologicum\r\n DP - 2024\r\n LA - en\r\n TI - Use of Laser Therapy for Peri-implantitis\r\nOWN - ITI International Team for Implantology\r\n AU - Fu K.\r\n AU - Chen Y.\r\n AU - Wang H.\r\nAID - 10.3290\/iti.fi.45738[doi]\r\n AB - Abstract"},"_links":{"self":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article"}],"about":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/types\/article"}],"version-history":[{"count":4,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/941\/revisions"}],"predecessor-version":[{"id":1910,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article\/941\/revisions\/1910"}],"acf:post":[{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1315"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1313"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-author\/1311"},{"embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/feature-topic\/1442"}],"wp:attachment":[{"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/media?parent=941"}],"wp:term":[{"taxonomy":"article-type","embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/article-type?post=941"},{"taxonomy":"forum-tag","embeddable":true,"href":"https:\/\/forum-impl.iti.org\/en\/wp-json\/wp\/v2\/forum-tag?post=941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}